Melanocortin receptors, red hair, and skin cancer.

@article{Rees1997MelanocortinRR,
  title={Melanocortin receptors, red hair, and skin cancer.},
  author={Jonathan Laurence Rees and Eugene Healy},
  journal={The journal of investigative dermatology. Symposium proceedings},
  year={1997},
  volume={2 1},
  pages={94-8}
}
Cutaneous pigmentation is a major determinant of the cutaneous response to ultraviolet radiation, and consequently of the risk of developing skin cancer. Over the past 10 years, several genes involved in melanogenesis have been identified, including the melanocortin 1 receptor gene. Recent work on the melanocortin 1 receptor suggests that it is a key player in determining whether eumelanin or pheomelanin is predominantly produced both in vitro and in vivo. In the mouse, variants of this… CONTINUE READING

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