Melanocortin receptor 1 (MC1R) mutations and coat color in pigs.

  title={Melanocortin receptor 1 (MC1R) mutations and coat color in pigs.},
  author={James MH Kijas and Richard Wales and Anna T{\"o}rnsten and P. Chardon and Michael Moller and Lars Andersson},
  volume={150 3},
The melanocortin receptor 1 (MC1R) plays a central role in regulation of eumelanin (black/brown) and phaeomelanin (red/yellow) synthesis within the mammalian melanocyte and is encoded by the classical Extension (E) coat color locus. Sequence analysis of MC1R from seven porcine breeds revealed a total of four allelic variants corresponding to five different E alleles. The European wild boar possessed a unique MC1R allele that we believe is required for the expression of a wild-type coat color… CONTINUE READING
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