Melanocortin-1 receptor-mediated signalling pathways activated by NDP-MSH and HBD3 ligands.

Abstract

Binding of melanocortin peptide agonists to the melanocortin-1 receptor of melanocytes results in eumelanin production, whereas binding of the agouti signalling protein inverse agonist results in pheomelanin synthesis. Recently, a novel melanocortin-1 receptor ligand was reported. A β-defensin gene mutation was found to be responsible for black coat colour… (More)
DOI: 10.1111/j.1755-148X.2012.00990.x

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@article{Beaumont2012Melanocortin1RS, title={Melanocortin-1 receptor-mediated signalling pathways activated by NDP-MSH and HBD3 ligands.}, author={Kimberley A. Beaumont and Darren J. Smit and Yan Yan Liu and Eric Chai and Mira P Patel and Glenn L. Millhauser and Jennifer J. Smith and Paul F Alewood and Richard A Sturm}, journal={Pigment cell & melanoma research}, year={2012}, volume={25 3}, pages={370-4} }