Melanin-producing medullary carcinoma of the thyroid gland. A case report.

  title={Melanin-producing medullary carcinoma of the thyroid gland. A case report.},
  author={Jennie Posen and D N Adamthwaite and H Greeff},
  journal={South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde},
  volume={65 2},
A case of melanin-producing medullary carcinoma of the thyroid gland is reported. The histological characteristics of the tumour were typical of medullary carcinoma, immunohistochemical testing for calcitonin was positive, and neurosecretory granules were found to be present on ultrastructural examination. In addition the tumour was producing melanin and melanosomes were identified in the same cells which contained neurosecretory granules, suggesting that the tumour arose from a common… CONTINUE READING
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