Melanin concentrating hormone (MCH): a novel neural pathway for regulation of GnRH neurons.

@article{WilliamsonHughes2005MelaninCH,
  title={Melanin concentrating hormone (MCH): a novel neural pathway for regulation of GnRH neurons.},
  author={Patricia S Williamson-Hughes and Kevin L. Grove and M Susan Smith},
  journal={Brain research},
  year={2005},
  volume={1041 2},
  pages={117-24}
}
The link between the state of energy balance and reproductive function is well known. Thus, signals denoting negative energy balance and the accompanying hyperphagic drive are likely to be factors in the suppression of gonadotropin releasing hormone (GnRH) activity. We have previously found that appetite-regulating systems, such as neuropeptide Y (NPY) in the arcuate nucleus (ARH) and orexin in the lateral hypothalamic area (LHA), send fiber projections that come in close apposition with GnRH… CONTINUE READING
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