Melanin biosynthesis patterns following hormonal stimulation.

@article{Aroca1993MelaninBP,
  title={Melanin biosynthesis patterns following hormonal stimulation.},
  author={Pilar Aroca and Kazunori Urabe and Tohru Kobayashi and Kentaro Tsukamoto and Vincent J. Hearing},
  journal={The Journal of biological chemistry},
  year={1993},
  volume={268 34},
  pages={
          25650-5
        }
}
The effect of melanocyte-stimulating hormone (MSH) on the differentiation of mammalian melanocytes has been widely studied since the early 1950s. There have been many reports about the stimulatory effect of MSH on melanin production and specifically on the activity of tyrosinase, the critical enzyme in the melanogenic pathway. However, few and variable results have been obtained concerning the effect of this hormone on the regulation of DOPAchrome tautomerase (TRP2), another melanogenic enzyme… CONTINUE READING
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