Melanin and melanosome complexes in long standing stable vitiligo--an ultrastructural study.

@article{Bartosik1998MelaninAM,
  title={Melanin and melanosome complexes in long standing stable vitiligo--an ultrastructural study.},
  author={Jacek Bartosik and Hans Christian Olsen Wulf and Takasi Kobayasi},
  journal={European journal of dermatology : EJD},
  year={1998},
  volume={8 2},
  pages={95-7}
}
To investigate the presence of melanin and melanocytes (MC) in stable vitiligo, skin biopsies from five patients with vitiligo lesions of between 1 to 17 years duration were examined under the electron microscope. Areas of the upper dermis and epidermis were explored. There was a significant amount of melanin in a few keratinocytes (KC) grouped in the stratum basale in 1-3 year-old vitiligo lesions. In these KC, the melanosomes were most often aggregated into melanosome complexes (MCo) while… CONTINUE READING