Melan A/MART-1 immunoreactivity in formalin-fixed paraffin-embedded primary and metastatic melanoma: frequency and distribution.

@article{Hofbauer1998MelanAI,
  title={Melan A/MART-1 immunoreactivity in formalin-fixed paraffin-embedded primary and metastatic melanoma: frequency and distribution.},
  author={G{\"u}nther F. L. Hofbauer and Jivko Kamarashev and Ralf Geertsen and R. A. Huch B{\"o}ni and Reinhard Dummer},
  journal={Melanoma research},
  year={1998},
  volume={8 4},
  pages={337-43}
}
Monoclonal antibody (MAb) A103 specifically detects Melan A/MART-1 protein expression. Melan A/MART-1-derived peptides are recognized by CD8+ T-cells and are used in immunotherapy. We examined formalin-fixed paraffin-embedded tissue from 57 melanomas (34 primary, 23 metastatic) and 39 control cases (junctional, dermal, compound, Spitz, Reed and balloon-cell naevi) using the alkaline phosphatase and anti-alkaline phosphatase immunochemical method after antigen retrieval. Immunoreactivity was… CONTINUE READING

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