Meiotic recombination, noncoding DNA and genomic organization in Caenorhabditis elegans.

@article{Barnes1995MeioticRN,
  title={Meiotic recombination, noncoding DNA and genomic organization in Caenorhabditis elegans.},
  author={Thomas M. Barnes and Yuji Kohara and Alan Coulson and Siegfried Hekimi},
  journal={Genetics},
  year={1995},
  volume={141 1},
  pages={159-79}
}
The genetic map of each Caenorhabditis elegans chromosome has a central gene cluster (less pronounced on the X chromosome) that contains most of the mutationally defined genes. Many linkage group termini also have clusters, though involving fewer loci. We examine the factors shaping the genetic map by analyzing the rate of recombination and gene density across the genome using the positions of cloned genes and random cDNA clones from the physical map. Each chromosome has a central gene-dense… CONTINUE READING
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