Meiotic defects in a man with non-obstructive azoospermia: case report.

@article{Sun2004MeioticDI,
  title={Meiotic defects in a man with non-obstructive azoospermia: case report.},
  author={Fei Sun and Graham Kozak and Sarah E. Scott and Kiril Trpkov and Evelyn Ko and Monica M. Mikhaail-Philips and Timothy H Bestor and Peter Moens and R. H. Martin},
  journal={Human reproduction},
  year={2004},
  volume={19 8},
  pages={1770-3}
}
Infertile men have an increased frequency of aneuploid sperm. We have determined that decreased recombination is associated with the production of aneuploid sperm in humans. The aim of this study was to determine whether some cases of infertility are associated with decreased meiotic recombination. Analysis of the early stages of meiosis was performed in a 33-year-old man with non-obstructive azoospermia. Newly developed immunocytogenetic techniques were used to identify the synaptonemal… CONTINUE READING