Meiotic crossing-over in lily and mouse

@article{Hotta1977MeioticCI,
  title={Meiotic crossing-over in lily and mouse},
  author={Yasuo Hotta and Ann C. Chandley and Herbert Stern},
  journal={Nature},
  year={1977},
  volume={269},
  pages={240-242}
}
CYTOLOGICAL descriptions of meiosis have long been a staple of biology textbooks, but a biochemical account of the process with a comparable claim to universality has been unavailable. We present here evidence for a common pattern of DNA metabolism in male meiotic cells of lilies and rodents during the zygotene–pachytene stages when crossing-over is presumed to occur. The prevalence of a common pattern between species that are as phylogenetically distant as lily and mouse has led us to conclude… 
The Use of Mutants in the Analysis of Meiosis
TLDR
Analysis of a large spectrum of mutants deficient in the various functions involved in normal meiotic progression and haploid progeny differentiation provides a fruitful approach to the study of meiotic-specific events and their regulation.
Side-by-side pairing of the XY bivalent in spermatocytes and the ubiquity of the H-Y locus.
  • L. Tres
  • Biology
    Archives of andrology
  • 1979
The pairing mechanism of the XY bivalent, the possibility of crossing-over between X and Y chromosomes during meiotic prophase, and the location of the H-Y locus are of interest with regard to
Absence of satellite DNA synthesis during meiotic prophase in mouse and human spermatocytes
TLDR
The absence of detectable pachytene synthesis in satellite DNA is consistent with genetic evidence on the absence of crossing-over in constitutive heterochromatin.
DNA sequences repaired at pachytene exhibit strong homology among distantly related higher plants
Moderately repetitive DNA sequences in Lilium (cv Enchantment) which undergo a meiotic-specific repair synthesis during pachytene (P-DNA) were previously shown to exist as families of very low
Hybrid dysgenesis in Drosophila: The mechanism of T-007-induced male recombination
TLDR
The results demonstrate that although some recombinants may be generated by nonhomologous chromosome (or chromatid) breakage and reunion, the predominant effect of T-007 is through an enhanced rate of normal mitotic exchange.
Satellite DNA and heterochromatin variants: The case for unequal mitotic crossing over
TLDR
A variety of molecular and cytogenetic evidence supports the hypothesis that heteromorphisms result from unequal double-strand exchanges during mitotic DNA replication, and variations of constitutive heterochromatin may be useful as markers of exposure to mutagens and/or carcinogens.
Higher levels of organization in chromosomes.
Two X family DNA polymerases, λ and μ, in meiotic tissues of the basidiomycete, Coprinus cinereus
TLDR
In analyses using D-loop recombination intermediate substrates, it is found that both CcPolλ andCcPolμ could promote primer extension of an invading strand in a D- loop structure, suggesting that D- Loop extension is an activity intrinsic to Cc Polλ and C cPolμ.
DNA synthesized at pachytene in Lilium: A non-divergent subclass of moderately repetitive sequences
TLDR
Calculations lead to the conclusion that pachytene middle repeat sequences account for 1% of the genome, ten times the previously estimated size.
...
...

References

SHOWING 1-10 OF 11 REFERENCES
Biochemistry of meiosis.
  • H. Stern, Y. Hotta
  • Biology
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  • 1977
TLDR
The temporal segregation of metabolic activities concerned with pairing and crossing over and their operation in special chromosome regions constitute the most prominent features of the biochemical events associated with meiosis.
Meiotic protein in spermatocytes of mammals.
TLDR
The DNA-binding protein in meiotic cells of Lilium has a very high binding affinity for single stranded DNA and also the unusual property of catalysing the renaturation of thermally denatured lily DNA at room temperature, which led to a more extensive study of its behaviour.
Repeated DNA synthesized during pachytene in Lilium henryi.
TLDR
In microsporocytes of Lilium, a repair synthesis of about 0.1% of the nuclear DNA occurs at this stage, separate from the pre-meiotic S-phase synthesis, reflecting limited repair at the breakpoints of DNA molecules involved in crossing over.
Correlated components of chiasma variation and the control of chiasma distribution in rye
TLDR
It is concluded that recombination is probably a two-step process in rye, as has been proposed for Dorsophila melanogaster, and that the rye distributional mutant lines are probably analogous to the so-called pre-condition mutants of Drosophila, that is they are defective in the establishment of exchange positions.
Single-strand scissions of chromosomal DNA during commitment to recombination at meiosis.
Diploid cells of the yeast Saccharomyces cerevisiae induced to undergo meiosis accumulate single-strand scissions in both template and newly synthesized DNA during commitment to genetic
A mechanism to activate branch migration between homologous DNA molecules in genetic recombination.
  • H. M. Sobell
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1975
TLDR
A mechanism to activate branch migration between homologous DNA molecules that leads to synapsis in genetic recombination and subsequent propagation of hybrid DNA in the pathway to formation of the synapton structure is described.
SEDIMENTATION STUDIES OF THE SIZE AND SHAPE OF DNA.
A mechanism for initiation of genetic recombination.
  • R. Wagner, M. Radman
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1975
A mechanism for the initiation of genetic recombination is proposed. Its key features are the pairing, nicking, and cross-annealing of palindromic loops, i.e., structures formed by DNA with sequences
...
...