Meiotic cell cycle arrest in mammalian oocytes

@article{Tripathi2010MeioticCC,
  title={Meiotic cell cycle arrest in mammalian oocytes},
  author={Anima Tripathi and K.V. Prem Kumar and Shail K Chaube},
  journal={Journal of Cellular Physiology},
  year={2010},
  volume={223}
}
Meiotic cell cycle in mammalian oocytes is a dynamic process that involves several stop/go channels. The cell cycle arrest in oocyte occurs at various stages such as diplotene, metaphase‐I (M‐I), metaphase‐II (M‐II), and so called metaphase‐like arrest (M‐III). Leutinizing hormone surge induces meiotic resumption from diplotene arrest in follicular microenvironment by overriding several factors responsible for the maintenance of meiotic arrest. The inhibitory factors are synthesized in oocyte… 

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