Meiotic anomalies in infertile men with severe spermatogenic defects.

  title={Meiotic anomalies in infertile men with severe spermatogenic defects.},
  author={M R Guichaoua and J Perrin and Catherine Metzler-Guillemain and Jacqueline Saias-Magnan and Roch Giorgi and Jean Marie Grillo},
  journal={Human reproduction},
  volume={20 7},
BACKGROUND This study was aimed at evaluating the rate of pairing failure in pachytene spermatocytes of patients presenting either an obstructive (O) or a non-obstructive (NO) infertility. METHODS Forty-one patients and 13 controls underwent testicular biopsy. Among the patients, 19 had an O infertility and 22 a NO infertility. Preparations of all patients and controls were Giemsa-stained, and synaptonemal complexes from nine of these patients and one control were immunostained. RESULTS In… CONTINUE READING