Meiotic Sex Chromosome Inactivation in Drosophila

  title={Meiotic Sex Chromosome Inactivation in Drosophila},
  author={Maria D. Vibranovski},
  booktitle={Journal of genomics},
In several different taxa, there is indubitable evidence of transcriptional silencing of the X and Y chromosomes in male meiotic cells of spermatogenesis. However, the so called meiotic sex chromosome inactivation (MSCI) has been recently a hot bed for debate in Drosophila melanogaster. This review covers cytological and genetic observations, data from transgenic constructs with testis-specific promoters, global expression profiles obtained from mutant, wild-type, larvae and adult testes as… CONTINUE READING
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The role of X-chromosome inactivation during spermatogenesis (Drosophila-allocycly-chromosome evolution-male sterility-dosage compensation).

Proceedings of the National Academy of Sciences of the United States of America • 1972
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