Meiosis and sex chromosome aneuploidy: how meiotic errors cause aneuploidy; how aneuploidy causes meiotic errors.

@article{Hall2006MeiosisAS,
  title={Meiosis and sex chromosome aneuploidy: how meiotic errors cause aneuploidy; how aneuploidy causes meiotic errors.},
  author={Heather E. Hall and Patricia A Hunt and Terry J. Hassold},
  journal={Current opinion in genetics & development},
  year={2006},
  volume={16 3},
  pages={323-9}
}
As a group, sex chromosome aneuploidies - the 47,XXY, 47,XYY, 47,XXX and 45,X conditions - constitute the most common class of chromosome abnormality in human live-births. Considerable attention has been given to the somatic abnormalities associated with these conditions, but less is known about their meiotic phenotypes; that is, how does sex chromosome imbalance influence the meiotic process. This has become more important with the advent of assisted reproductive technologies, because… CONTINUE READING
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