Meiosis I chromosome segregation is established through regulation of microtubule–kinetochore interactions

@inproceedings{Miller2012MeiosisIC,
  title={Meiosis I chromosome segregation is established through regulation of microtubule–kinetochore interactions},
  author={Matthew P Miller and Elçin {\"U}nal and Gloria Ann Brar and Angelika Amon},
  booktitle={eLife},
  year={2012}
}
During meiosis, a single round of DNA replication is followed by two consecutive rounds of nuclear divisions called meiosis I and meiosis II. In meiosis I, homologous chromosomes segregate, while sister chromatids remain together. Determining how this unusual chromosome segregation behavior is established is central to understanding germ cell development. Here we show that preventing microtubule-kinetochore interactions during premeiotic S phase and prophase I is essential for establishing the… CONTINUE READING
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