Megavoltage pituitary irradiation in the management of prolactinomas: long-term follow-up.

@article{Tsagarakis1991MegavoltagePI,
  title={Megavoltage pituitary irradiation in the management of prolactinomas: long-term follow-up.},
  author={Stenlios Tsagarakis and Ashley Grossman and Piers Nicholas Plowman and Alan E. Jones and R J Touzel and Lesley H. Rees and John A.H. Wass and G. Michael Besser},
  journal={Clinical endocrinology},
  year={1991},
  volume={34 5},
  pages={399-406}
}
OBJECTIVE To determine the long-term effects of external beam megavoltage radiotherapy (RT: 4500 cGy via three portals at 180 cGy or less total daily dose) on endocrine function in prolactinomas. DESIGN Longitudinal study following radiotherapy with periodic re-assessment at regular intervals, at least 2 months off dopamine agonist therapy. PATIENTS Thirty-six female patients, age range 19-50 years, with either macroprolactinomas (12 patients) or microprolactinomas (24 patients), but without… CONTINUE READING
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