Megalin and cubilin in the human gallbladder epithelium

  title={Megalin and cubilin in the human gallbladder epithelium},
  author={Alexandra K. Tsaroucha and Ekaterini Chatzaki and Maria Lambropoulou and Kaliopi Despoudi and Prodromos Laftsidis and Chara Charsou and Alexandros Ch Polychronidis and Nikolaos E. Papadopoulos and Constantinos E. Simopoulos},
  journal={Clinical and Experimental Medicine},
Although the role of cholesterol absorption by the gallbladder epithelium in gallstone formation is well established, the exact process is poorly understood. Potential candidates for regulation of transepithelial cholesterol transport are suggested to be two large membrane multiple ligand receptors, megalin and cubilin. We studied the expression of these two proteins in both acalculous and calculous human gallbladder epithelia. Adult human gallbladder tissues were received from 21 patients (9… CONTINUE READING


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