Megakaryocyte potentiation factor cleaved from mesothelin precursor is a useful tumor marker in the serum of patients with mesothelioma.

@article{Onda2006MegakaryocytePF,
  title={Megakaryocyte potentiation factor cleaved from mesothelin precursor is a useful tumor marker in the serum of patients with mesothelioma.},
  author={Masanori Onda and Satoshi Nagata and M. Ho and Tapan Kumar Bera and Raffit Hassan and Richard H. Alexander and Ira Pastan},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2006},
  volume={12 14 Pt 1},
  pages={4225-31}
}
PURPOSE To establish monoclonal antibodies (mAb) against megakaryocyte potentiation factor (MPF) and detect MPF in the blood of patients with mesothelioma. EXPERIMENTAL DESIGN Mice were immunized with a purified recombinant human MPF-rabbit-Fc fusion protein and with MPF. Several hybridomas producing mAbs to MPF were established. A double-determinant… CONTINUE READING