Mefenamic Acid Attenuates Intracerebroventricular Streptozotocin-Induced Cognitive Deficits in the Rat : A Behavioral Analysis

Intracerebroventricular (ICV) injection of streptozotocin (STZ) in rats is followed by long-term and progressive deficits in learning, memory, and cognitive performance in rats which is somewhat similar to sporadic Alzheimer’s disease (SAD). Epidemiological studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs) could delay or slow the clinical… CONTINUE READING