Meeting the Challenges of Non-Referenced Genome Assembly from Short-Read Sequence Data

@inproceedings{Parks2010MeetingTC,
  title={Meeting the Challenges of Non-Referenced Genome Assembly from Short-Read Sequence Data},
  author={Matthew Parks and Aaron Liston and Richard Cronn},
  year={2010}
}
Massively parallel sequencing technologies (MPST) offer unprecedented opportunities for novel sequencing projects. MPST, while offering tremendous sequencing capacity, are typically most effective in resequencing projects (as opposed to the sequencing of novel genomes) due to the fact that sequence is returned in relatively short reads. Nonetheless, there is great interest in applying MPST to genome sequencing in non-model organisms. We have developed a bioinformatics pipeline to assemble short… CONTINUE READING

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