Medulloblastoma as a secondary malignancy after radiotherapy-free treatment for acute lymphoblastic leukemia.


Malignant brain tumors have been reported to occur in survivors of childhood acute lymphoblastic leukemia (ALL) more frequently than in the noncancer control population. The strongest risk factor seems to be cranial radiotherapy, used as central nervous system (CNS) prophylaxis. We report the case of a 9-year-old girl affected with metastatic… (More)


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