Medulloblastoma: clinical and biologic aspects.

  title={Medulloblastoma: clinical and biologic aspects.},
  author={Roger J. Packer and Philip Cogen and Gilbert Vezina and Lucy Balian Rorke},
  volume={1 3},
Medulloblastoma is the most common childhood primary CNS tumor, and treatment approaches have evolved over the past three decades. The biologic underpinnings of medulloblastoma are not fully characterized, but recent work has identified new, important directions for research. Stratification of patients with medulloblastoma into risk groups is the backbone of most ongoing therapeutic studies. Patients are usually characterized as being either average risk or poor risk, although an intermediate… CONTINUE READING


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