Medullary carcinoma of the thyroid gland.

@article{Shapiro1976MedullaryCO,
  title={Medullary carcinoma of the thyroid gland.},
  author={Marc Shapiro},
  journal={The Laryngoscope},
  year={1976},
  volume={86 9},
  pages={1375-85}
}
Endocrine as well as oncologic attributes mark this rare tumor as unique. It is derived from "C cells" resembling the parafollicular cells of lower animals; these cells elaborate Calcitonin which acts as a sensitive signal of the presence of the tumor. Other endocrinopathies are present in 70 percent of cases so that the tumor may present as part of a complex but increasing well known clinical picture. In 10 percent the tumor occurs as an autosomal dominant trait; in the remainder, the… CONTINUE READING
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