Medium with blood-analog mechanical properties for cardiovascular tissue culturing.

@article{Broek2008MediumWB,
  title={Medium with blood-analog mechanical properties for cardiovascular tissue culturing.},
  author={Chantal N van den Broek and Rolf A A Pullens and Ole Fr{\o}bert and Marcel C. M. Rutten and Wilfred F den Hartog and Frans N. van De Vosse},
  journal={Biorheology},
  year={2008},
  volume={45 6},
  pages={
          651-61
        }
}
Physiological wall shear rates and stresses in vessel culture or tissue engineering are relevant for maintaining endothelial cell (EC) integrity. To this end, the culture medium should have an appropriate viscosity. The viscosity of a standard culture medium was increased using xanthan gum (XG) and compared with literature data on whole blood, resulting in a medium with blood-analog shear-thinning behavior (XG-medium). The measured osmolality of the XG-medium was 285+/-2 mOsm kg(-1), which is… CONTINUE READING

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