Medium-term effectiveness of L-thyroxine treatment in idiopathic dilated cardiomyopathy.

  title={Medium-term effectiveness of L-thyroxine treatment in idiopathic dilated cardiomyopathy.},
  author={Paolo Moruzzi and Elisabetta Doria and Piergiuseppe Agostoni},
  journal={The American journal of medicine},
  volume={101 5},
BACKGROUND In dilated cardiomyopathy, short-term administration of L-thyroxine (100 micrograms/ day) improves cardiac and exercise performance without changing the heart's adrenergic sensitivity. The aim of this study was to test the medium-term (3 months) efficacy of L-thyroxine (10 patients) compared with placebo (10 patients) and to find out whether later effects are obtainable. METHODS Echocardiographic parameters in the control state and during acute changes of left ventricular afterload… CONTINUE READING
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