Medium-dose-rate brachytherapy of cancer of the cervix: preliminary results of a prospectively designed schedule based on the linear-quadratic model.

@article{LeBorgne1999MediumdoserateBO,
  title={Medium-dose-rate brachytherapy of cancer of the cervix: preliminary results of a prospectively designed schedule based on the linear-quadratic model.},
  author={F. LeBorgne and John F. Fowler and Jos{\'e} H Leborgne and Eduardo H Zubizarreta and R Curochquin},
  journal={International journal of radiation oncology, biology, physics},
  year={1999},
  volume={43 5},
  pages={1061-4}
}
PURPOSE To compare results and complications of our previous low-dose-rate (LDR) brachytherapy schedule for early-stage cancer of the cervix, with a prospectively designed medium-dose-rate (MDR) schedule, based on the linear-quadratic model (LQ). METHODS AND MATERIALS A combination of brachytherapy, external beam pelvic and parametrial irradiation was used in 102 consecutive Stage Ib-IIb LDR treated patients (1986-1990) and 42 equally staged MDR treated patients (1994-1996). The planned MDR… CONTINUE READING

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The planned MDR schedule consisted of three insertions on three treatment days with six 8-Gy brachytherapy fractions to Point A , two on each treatment day with an interfraction interval of 6 hours , plus 18 Gy external whole pelvic dose , and followed by additional parametrial irradiation .
A combination of brachytherapy , external beam pelvic and parametrial irradiation was used in 102 consecutive Stage Ib - IIb LDR treated patients ( 1986 - 1990 ) and 42 equally staged MDR treated patients ( 1994 - 1996 ) .
The planned MDR schedule consisted of three insertions on three treatment days with six 8-Gy brachytherapy fractions to Point A , two on each treatment day with an interfraction interval of 6 hours , plus 18 Gy external whole pelvic dose , and followed by additional parametrial irradiation .
A combination of brachytherapy , external beam pelvic and parametrial irradiation was used in 102 consecutive Stage Ib - IIb LDR treated patients ( 1986 - 1990 ) and 42 equally staged MDR treated patients ( 1994 - 1996 ) .
The planned MDR schedule consisted of three insertions on three treatment days with six 8-Gy brachytherapy fractions to Point A , two on each treatment day with an interfraction interval of 6 hours , plus 18 Gy external whole pelvic dose , and followed by additional parametrial irradiation .
A combination of brachytherapy , external beam pelvic and parametrial irradiation was used in 102 consecutive Stage Ib - IIb LDR treated patients ( 1986 - 1990 ) and 42 equally staged MDR treated patients ( 1994 - 1996 ) .
The planned MDR schedule consisted of three insertions on three treatment days with six 8-Gy brachytherapy fractions to Point A , two on each treatment day with an interfraction interval of 6 hours , plus 18 Gy external whole pelvic dose , and followed by additional parametrial irradiation .
A combination of brachytherapy , external beam pelvic and parametrial irradiation was used in 102 consecutive Stage Ib - IIb LDR treated patients ( 1986 - 1990 ) and 42 equally staged MDR treated patients ( 1994 - 1996 ) .
The planned MDR schedule consisted of three insertions on three treatment days with six 8-Gy brachytherapy fractions to Point A , two on each treatment day with an interfraction interval of 6 hours , plus 18 Gy external whole pelvic dose , and followed by additional parametrial irradiation .
A combination of brachytherapy , external beam pelvic and parametrial irradiation was used in 102 consecutive Stage Ib - IIb LDR treated patients ( 1986 - 1990 ) and 42 equally staged MDR treated patients ( 1994 - 1996 ) .
The planned MDR schedule consisted of three insertions on three treatment days with six 8-Gy brachytherapy fractions to Point A , two on each treatment day with an interfraction interval of 6 hours , plus 18 Gy external whole pelvic dose , and followed by additional parametrial irradiation .
A combination of brachytherapy , external beam pelvic and parametrial irradiation was used in 102 consecutive Stage Ib - IIb LDR treated patients ( 1986 - 1990 ) and 42 equally staged MDR treated patients ( 1994 - 1996 ) .
The planned MDR schedule consisted of three insertions on three treatment days with six 8-Gy brachytherapy fractions to Point A , two on each treatment day with an interfraction interval of 6 hours , plus 18 Gy external whole pelvic dose , and followed by additional parametrial irradiation .
A combination of brachytherapy , external beam pelvic and parametrial irradiation was used in 102 consecutive Stage Ib - IIb LDR treated patients ( 1986 - 1990 ) and 42 equally staged MDR treated patients ( 1994 - 1996 ) .
The planned MDR schedule consisted of three insertions on three treatment days with six 8-Gy brachytherapy fractions to Point A , two on each treatment day with an interfraction interval of 6 hours , plus 18 Gy external whole pelvic dose , and followed by additional parametrial irradiation .
A combination of brachytherapy , external beam pelvic and parametrial irradiation was used in 102 consecutive Stage Ib - IIb LDR treated patients ( 1986 - 1990 ) and 42 equally staged MDR treated patients ( 1994 - 1996 ) .
The planned MDR schedule consisted of three insertions on three treatment days with six 8-Gy brachytherapy fractions to Point A , two on each treatment day with an interfraction interval of 6 hours , plus 18 Gy external whole pelvic dose , and followed by additional parametrial irradiation .
A combination of brachytherapy , external beam pelvic and parametrial irradiation was used in 102 consecutive Stage Ib - IIb LDR treated patients ( 1986 - 1990 ) and 42 equally staged MDR treated patients ( 1994 - 1996 ) .
The planned MDR schedule consisted of three insertions on three treatment days with six 8-Gy brachytherapy fractions to Point A , two on each treatment day with an interfraction interval of 6 hours , plus 18 Gy external whole pelvic dose , and followed by additional parametrial irradiation .
A combination of brachytherapy , external beam pelvic and parametrial irradiation was used in 102 consecutive Stage Ib - IIb LDR treated patients ( 1986 - 1990 ) and 42 equally staged MDR treated patients ( 1994 - 1996 ) .
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