Medium-chain triglycerides are advantageous in promoting weight loss although not beneficial to exercise performance

@article{Clegg2010MediumchainTA,
  title={Medium-chain triglycerides are advantageous in promoting weight loss although not beneficial to exercise performance},
  author={Miriam E. Clegg},
  journal={International Journal of Food Sciences and Nutrition},
  year={2010},
  volume={61},
  pages={653 - 679}
}
  • M. Clegg
  • Published 2010
  • Chemistry, Medicine
  • International Journal of Food Sciences and Nutrition
Medium-chain triglycerides (MCT) are triglycerides with a fatty acid chain length varying between 6 and 10 carbon atoms. MCT differ from long-chain triglycerides as they are relatively soluble in water and, hence, rapidly hydrolysed and absorbed. MCT are transported in the blood through the portal system, consequently they bypass adipose tissue that makes them less susceptible to hormone-sensitive lipase and deposition into adipose tissue stores. Due to these properties, MCT have been… Expand
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TLDR
This review encompasses most aspects of MCT metabolism arguing this slimming hypothesis pro and con, and concludes that long-term compliance to such slimming regimens is unlikely in human nutrition. Expand
Structured medium and long chain triglycerides show short-term increases in fat oxidation, but no changes in adiposity in men.
TLDR
The present structured medium and long chain triglyceride oil increases short-term fat oxidation but fails to modulate body weight or adiposity through a change in EE. Expand
Greater rise in fat oxidation with medium-chain triglyceride consumption relative to long-chain triglyceride is associated with lower initial body weight and greater loss of subcutaneous adipose tissue
TLDR
It is suggested that shunting of dietary fat towards oxidation results in diminished fat storage, as reflected by the loss of BW and subcutaneous adipose tissue. Expand
Medium-chain triglycerides increase energy expenditure and decrease adiposity in overweight men.
TLDR
Consumption of a diet rich in MCTs results in greater loss of AT compared with LCTs, perhaps due to increased energy expenditure and fat oxidation observed with MCT intake, which may help in the prevention of obesity or potentially stimulate weight loss. Expand
Medium- versus long-chain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting in changes in body composition in overweight women
OBJECTIVE: To determine the effects of long-term consumption of medium chain (MCT) versus long chain triglycerides (LCT) on energy expenditure (EE), substrate oxidation and bodyExpand
Value of VLCD supplementation with medium chain triglycerides
TLDR
Replacement of LCT by MCT in the VLCD increased the rate of decrease of body fat and body weight and has a sparing effect on FFM. Expand
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TLDR
From the literature reviewed, it is concluded that MCT increase energy expenditure, may result in faster satiety and facilitate weight control when included in the diet as a replacement for fats containing LCT. Expand
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TLDR
The changes in fatty acids in triglycerides with MCT feeding are consistent with the hypothesis that excess dietary MCT cause a significant increase in the hepatic synthesis of these fatty acids from MCFA through de novo synthesis and/or chain elongation and desaturation. Expand
Combined intervention of medium-chain triacylglycerol diet and exercise reduces body fat mass and enhances energy expenditure in rats.
TLDR
It is suggested that combined intervention of MCT diet and exercise has an additive effect on reduction of visceral and subcutaneous fat accumulation, and that this effect may be partially related to increased energy expenditure. Expand
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TLDR
The capacity of MCT to increase endogenous oxidation of LCSFA suggests a role for MCT in body weight control over the long term. Expand
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