Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study.

@article{deLorgeril1999MediterraneanDT,
  title={Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study.},
  author={Michel de Lorgeril and Patricia Salen and J. L. Mart{\'i}n and I Monjaud and Jacques Delaye and Nicole Mamelle},
  journal={Circulation},
  year={1999},
  volume={99 6},
  pages={
          779-85
        }
}
BACKGROUND The Lyon Diet Heart Study is a randomized secondary prevention trial aimed at testing whether a Mediterranean-type diet may reduce the rate of recurrence after a first myocardial infarction. [] Key Result In the Mediterranean diet group, CO 1 was reduced (14 events versus 44 in the prudent Western-type diet group, P=0.0001), as were CO 2 (27 events versus 90, P=0.0001) and CO 3 (95 events versus 180, P=0. 0002). Adjusted risk ratios ranged from 0.28 to 0.53.

Mediterranean-style diet is associated with reduced blood pressure variability and subsequent stroke risk in patients with coronary artery disease.

Among patients with CAD, a higher MDS is associated with a lower visit-to-visit BPV and with lower stroke risk, and a high MDS was an independent predictor for low systolic BPV.

The Efficacy of a Mediterranean Diet in Reducing the Risk of Cardiovascular and Cerebrovascular Disease Incidence and Mortality in Patients with Known Risk Factors

The Mediterranean diet has been shown to reduce the risk of cardiovascular disease incidence and mortality, and providers should advise patients without disease but with known risk factors to implement complete adherence to the Mediterranean diet for best risk reduction.

Primary prevention of cardiovascular disease with a Mediterranean diet.

Among persons at high cardiovascular risk, a Mediterranean diet supplemented with extra-virgin olive oil or nuts reduced the incidence of major cardiovascular events.

The Mediterranean-style diet for the prevention of cardiovascular diseases

Even small doses of omega-3 fatty acids might be very protective in the context of a diet rich in oleic acid, poor in saturated fats and low in omega-6 fatty acids (a dietary pattern characterising the traditional Mediterranean diet), underline the importance of the accompanying diet in any dietary strategy using fatty acid complements.

Dietary prevention of coronary heart disease: the Lyon Diet Heart Study.

The 46-month mean follow-up findings on the original report of the study on “Mediterranean α-linolenic acid–rich diet in secondary prevention of coronary heart disease,” the so-called Lyon Diet Heart Study, report the initial remarkably beneficial effects of the experimental dietary program persisted.

A Mediterranean-style diet, its components and the risk of heart failure: a prospective population-based study in a non-Mediterranean country

The tMED was not significantly associated withHF risk, but low meat, high fish and moderate alcohol intake were inversely associated with HF risk in the non-Mediterranean population.

Mediterranean diet adherence and synergy with acute myocardial infarction and its determinants: A multicenter case-control study in Italy

A synergistic effect does exist between poor adherence to the MD and the following risk factors: hypertension, hypercholesterolemia, BMI >25, diabetes and being a resident in central and northern Italy.
...

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