Medicinal use of the unique plant Tinospora Cordifolia: evidence from the traditional medicine and recent research

  title={Medicinal use of the unique plant Tinospora Cordifolia: evidence from the traditional medicine and recent research},
  author={Moniruzzaman Khan and M. Haque and S. I. Chowdhury},
  journal={Asian Journal of Medical and Biological Research},
Tinospora cordifolia is commonly known as Gulancha in Bangladesh is belongs to Menispermaceae family and it is also available all over the world. It is widely used as a unique ingredient of various natural medicine and traditionally use for numerous aliment like fever, vomiting, diabetes, jaundice, anaemia, polyuria and skin diseases etc. It has hypoglycemic, antipyretic, anti-allergic, Antineoplastic, anti inflammatory, antioxidant, and immuno modulatory properties. A variety of constituents… Expand
The chemical constituents and diverse pharmacological importance of Tinospora cordifolia
The present review highlights the pharmacological importance of Tinospora cordifolia viz antioxidant activity, antimicrobial activity, antibacterial activity, antifungal activity, anti-diabetic activity, anticancer anti HIV potential, antiosteoporotic effects, antitoxic effects, wound healing, anticomplementary activity, and immunomodulating activity, systemic infection and Parkinson's disease. Expand
Magical bullets from an indigenous Indian medicinal plant Tinospora cordifolia: An in silico approach for the antidote of SARS-CoV-2☆
Out of five standard drug molecules, two widely used antiviral drugs (Favipiravir and Remdesivir) are ascribed as the most potent molecules based on their highest docking score in the present study. Expand
Pritika Himalayan Journal of Health Sciences ISSN: 2582-0737
Immunomodulator can be defined as, any drug or its chemical constituents which can stimulate any component or function of the immune system in a specific or nonspecific way. This concept ofExpand
Herbal Decoction Divya-Peedantak-Kwath Alleviates Allodynia and Hyperalgesia in Mice Model of Chemotherapy-Induced Peripheral Neuropathy via Modulation in Cytokine Response
It is evinced that DPK can alleviate CIPN by attenuating oxidative stress and concomitant neuroinflammation through immune modulation, and acts as a nociceptive modulator for CIPn. Expand
Molecular Docking Studies and Anti-Alzheimer’s Potential of Isolated Compounds from Tinospora cordifolia
Abstract Inhibition of acetylcholinesterase (AChE) is a promising strategy for the management of Alzheimer’s disease (AD). Prolyl endopeptidase (PEP) is a post-proline cleaving enzyme that plays anExpand


Chemistry and medicinal properties of Tinospora cordifolia (Guduchi)
Tinospora cordifolia (Guduchi) is a widely used shrub in folk and ayurvedic systems of medicine. This review presents a detailed survey of the literature on chemistry and medicinal properties ofExpand
A Review on Tinospora Cordifolia
Tinospora.cordifolia (Gulancha) is an available and well known herb all over the world. It is traditionally use for various aliment like fever, vomiting, diabetes, jaundice, anaemia, polyuria andExpand
The last decade has seen a global upsurge in the use of traditional medicine (TM) and complementary and alternative medicines (CAM) in both developed and developing countries. Various forms ofExpand
A critical review on biological description and chemical constituents of T. cordifolia with special emphasis on its ayurvedic properties and applications in the pharmaceutical sector is presented. Expand
Evaluation of Antioxidant activity of traditional formulation Giloy satva and hydroalcoholic extract of the Curculigo orchioides gaertn
Herbal plants produce a diverse range of bioactive molecules, making them a rich source of different types of medicines. Thus, a proper scientific evidence or assessment has become the criteria forExpand
Hypoglycaemic and other related actions of Tinospora cordifolia roots in alloxan-induced diabetic rats.
Oral administration of an aqueous T. cordifolia root extract to alloxan diabetic rats caused a significant reduction in blood glucose and brain lipids and the extract caused an increase in body weight, total haemoglobin and hepatic hexokinase. Expand
Modulation of morphology and some gluconeogenic enzymes ac-tivity by Tinospora cordifolia (Willd.) in diabetic rat kidney
Drug treated diabetic animals showed a significant effect (p< 0.05) of TC on all these parameters except renal morphology, compared to untreated animals, showing that TC administration is safe in normal animals. Expand
Immunomodulatory and Antitumor Actions of Medicinal Plant Tinospora cordifolia Are Mediated Through Activation of Tumor‐Associated Macrophages
This is the first study of it's kind regarding the effect of alcoholic extract of Tinospora cordifolia on the activation of tumor associated macrophages and showing the antitumor effect on the spontaneous T‐cell lymphoma (DL), thus may have clinical implications. Expand
Antifertility effect of Tinospora cordifolia (Willd.) stem extract in male rats.
Sperm motility as well as sperm density were reduced significantly which resulted in reduction of male fertility by 100%, suggesting antifertility effects of the stem extract of T. cordifolia in male rats. Expand
Evaluation of the antiosteoporotic potential of Tinospora cordifolia in female rats.
It is demonstrated that extract of T. cordifolia has the potential for being used as antiosteoporotic agent and showed estrogen like effects in bone but not in reproductive organs like uterus and mammary gland. Expand