Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides

  title={Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides},
  author={Solomon P. Wasser},
  journal={Applied Microbiology and Biotechnology},
  • S. Wasser
  • Published 1 November 2002
  • Biology, Medicine
  • Applied Microbiology and Biotechnology
Abstract. [] Key Result These polysaccharides are of different chemical composition, with most belonging to the group of β-glucans; these have β-(1→3) linkages in the main chain of the glucan and additional β-(1→6) branch points that are needed for their antitumor action. High molecular weight glucans appear to be more effective than those of low molecular weight. Chemical modification is often carried out to improve the antitumor activity of polysaccharides and their clinical qualities (mostly water…

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The use of mushroom glucans and proteoglycans in cancer treatment.

  • P. Kidd
  • Medicine, Biology
    Alternative medicine review : a journal of clinical therapeutic
  • 2000
Two proteoglycans from Coriolus versicolor - PSK and PSP - have demonstrated the most promise and their extremely high tolerability, proven benefits to survival and quality of life, and compatibility with chemotherapy and radiation therapy makes them well suited for cancer management regimens.

Antitumor active protein-containing glycans from the Chinese mushroom songshan lingzhi, Ganoderma tsugae mycelium.

A water-soluble polysaccharide, FI, extracted from the mycelium of Granoderma tsugae, was fractionated and purified by ion-exchange chromatography, gel filtration, and affinity chromatography for antitumor effects on Sarcoma 180 in mice.

Polysaccharides in fungi. XXIX. Structural features of two antitumor polysaccharides from the fruiting bodies of Armillariella tabescens.

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Polysaccharides in Fungi. XXXIV. A polysaccharide from the fruiting bodies of Amanita muscaria and the antitumor activity of its carboxymethylated product.

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Antitumor activity of some polysaccharides isolated from a Chinese mushroom, "huangmo", the fruiting body of Hohenbuehelia serotina.

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