Medicinal attributes of pyrazolo[3,4-d]pyrimidines: a review.

  title={Medicinal attributes of pyrazolo[3,4-d]pyrimidines: a review.},
  author={Monika Chauhan and Raj Kumar},
  journal={Bioorganic & medicinal chemistry},
  volume={21 18},
Pyrazolopyrimidines are the fused heterocyclic ring systems which structurally resemble purines which prompted biological investigations to assess their potential therapeutic significance. They are known to play a crucial role in numerous disease conditions. The advent of their first bioactivity as adenosine antagonistic property divulged their medicinal potential. Radioactivity test on mice cells, morphometric and serological tests on rat hepatocytes, antitumor testing against L1210 and P388… CONTINUE READING


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Medicinal attributes of pyrazolo[3,4-d]pyrimidines: A review, Bioorganic & Medicinal Chemistry (2013), doi: This is a PDF file of an unedited manuscript

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