Medication Overuse Headache: History, Features, Prevention and Management Strategies

@article{Saper2013MedicationOH,
  title={Medication Overuse Headache: History, Features, Prevention and Management Strategies},
  author={J. Saper and A. N. Da Silva},
  journal={CNS Drugs},
  year={2013},
  volume={27},
  pages={867-877}
}
Medication overuse headache (MOH) is a daily, or almost daily, headache form that arises from overuse of one or more classes of migraine-abortive or analgesic medication. The main classes of drugs that cause MOH are opioids, butalbital-containing mixed analgesics, triptans, ergotamine tartrate derivatives, simple analgesics (except for plain aspirin), and perhaps non-steroidal anti-inflammatory drugs. MOH can be debilitating and results from biochemical and functional brain changes induced by… Expand
Medication Overuse Headache
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MOH can severely impact quality of life, so it is important to identify patients who are at risk of analgesic overuse and stop the offending drug(s), rescue therapy for withdrawal symptoms and preventative therapy. Expand
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TLDR
This narrative review describes how to try to prevent the development of MOH and how to manage it once it has appeared, and detects disease biomarkers and predictive factors for drug response that allow for personalized treatment when migraine is still episodic and make analgesic overuse pointless. Expand
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TLDR
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TLDR
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TLDR
Fremanezumab reduced the need for acute headache medications, including migraine-specific medications, while treating migraine-associated symptoms in patients with episodic migraine. Expand
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