Medication Adherence: Tailoring the Analysis to the Data

@article{Saberi2011MedicationAT,
  title={Medication Adherence: Tailoring the Analysis to the Data},
  author={Parya Saberi and Mallory O Johnson and Charles E Mcculloch and Eric Vittinghoff and Torsten B Neilands},
  journal={AIDS and Behavior},
  year={2011},
  volume={15},
  pages={1447-1453}
}
The purpose of this paper is to explore more comprehensive methods to analyze antiretroviral non-adherence data. Using illustrative data and simulations, we investigated the value of using binary logistic regression (LR; dichotomized at 0% non-adherence) versus a hurdle model (combination of LR plus generalized linear model for >0% non-adherence) versus a zero-inflated negative binomial (ZINB) model (simultaneously modeling 0% non-adherence and >0% non-adherence). In simulation studies, the… CONTINUE READING
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