Medically induced euthyroid hypothyroxinemia may extend survival in compassionate need cancer patients: an observational study.

@article{Hercbergs2015MedicallyIE,
  title={Medically induced euthyroid hypothyroxinemia may extend survival in compassionate need cancer patients: an observational study.},
  author={Aleck A. Hercbergs and Rebecca E Johnson and Osnat Ashur-Fabian and David Garfield and Paul J. Davis},
  journal={The oncologist},
  year={2015},
  volume={20 1},
  pages={72-6}
}
BACKGROUND Clinical studies have shown that interventional lowering of serum free thyroxine (FT4) may be associated with extended survival in patients with some terminal cancers. The report of success with this approach in glioblastoma multiforme caused involvement of the author (A.H.) in the prospective consultative management of 23 end-stage solid tumor patients in whom hypothyroxinemia was induced to prolong life. PATIENTS AND METHODS Patients were self-referred or recommended by attending… CONTINUE READING

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