Medical treatment of hepatocellular carcinoma.

  title={Medical treatment of hepatocellular carcinoma.},
  author={Domenico Germano and Vincenza Tinessa and Emiddio Barletta and Lucia Cannella and Bruno Daniele},
  journal={Minerva medica},
  volume={104 5},
The management of hepatocellular carcinoma (HCC) has substantially changed in the past few decades, the introduction of novel therapies (such as sorafenib) have improved patient survival. Nevertheless, HCC remains the third most common cause of cancer-related deaths worldwide. Decision-making largely relies on evidence-based criteria, as showed in the US and European clinical practice guidelines, which endorse five therapeutic recommendations: resection; transplantation; radiofrequency ablation… CONTINUE READING