Medical therapy of unstable angina pectoris.


The pathophysiologic mechanisms responsible for the clinical syndrome known as unstable angina pectoris are complex but provide a framework for a rational medical approach to this ischemic condition. The combined use of nitrates, beta-blockers, calcium antagonists, antiplatelet agents, and anticoagulants has been shown to reduce recurrent ischemia, and the latter therapies have reduced the incidence of progression to myocardial infarction and death. A rational risk stratification scheme, which utilizes the presenting symptoms, electrocardiographic, and anatomic information to identify patients for whom additional revascularization procedures are warranted, is presented.

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@article{Gottlieb1991MedicalTO, title={Medical therapy of unstable angina pectoris.}, author={Sidney O Gottlieb and John T. Flaherty}, journal={Cardiology clinics}, year={1991}, volume={9 1}, pages={89-98} }