Medical significance of peroxisome proliferator-activated receptors.

@article{Vamecq1999MedicalSO,
  title={Medical significance of peroxisome proliferator-activated receptors.},
  author={Joseph Vamecq and Norbert Latruffe},
  journal={Lancet},
  year={1999},
  volume={354 9173},
  pages={141-8}
}
Peroxisome proliferator-activated receptors (PPAR) were discovered in 1990, ending 25 years of uncertainty about the molecular mechanisms of peroxisome proliferation. Subsequently, PPARs have improved our understanding of adipocyte differentiation. But there is more to PPARs than solving a puzzle about an organelle (the peroxisome) long considered an oddity, and their medical significance goes beyond obesity too. Enhanced PPAR type alpha expression protects against cardiovascular disorders… CONTINUE READING

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