Medical interventions for the prevention of platinum-induced hearing loss in children with cancer.

@article{As2019MedicalIF,
  title={Medical interventions for the prevention of platinum-induced hearing loss in children with cancer.},
  author={Jorrit W van As and H. van den Berg and E. C. van Dalen},
  journal={The Cochrane database of systematic reviews},
  year={2019},
  volume={5},
  pages={
          CD009219
        }
}
  • Jorrit W van As, H. van den Berg, E. C. van Dalen
  • Published 2019
  • Medicine
  • The Cochrane database of systematic reviews
  • BACKGROUND Platinum-based therapy, including cisplatin, carboplatin, oxaliplatin or a combination of these, is used to treat a variety of paediatric malignancies. One of the most significant adverse effects is the occurrence of hearing loss or ototoxicity. In an effort to prevent this ototoxicity, different otoprotective medical interventions have been studied. This review is the third update of a previously published Cochrane Review. OBJECTIVES To assess the efficacy of medical interventions… CONTINUE READING