Soup or Sparks: The History of Drugs and Synapses
Understanding how drugs work at synapses led to new drugs and advances in health care—a stunning record of achievement.
Subjective, individual and aggregate references in educational research
Subjective, individual, and aggregate references in educational research are distinguished. A particular method may center around a particular type of reference. Uses and misuses are described.…
Circadian Effects of Drug Responses
- BiologyAnnual review of biomedical engineering
A holistic view of the therapeutic process is presented, discussing components such as disease state, pharmacokinetics, and pharmacodynamics, as well as adverse reactions that are critically affected by circadian rhythms.
Toxina botulínica tipo A: propriedades farmacológicas e uso clínico
- MedicineActa Fisiátrica
Todas as informações contidas neste trabalho de revisão são referentes a toxina botulínica do tipo A (TBA) produzida por Allergan Inc, representada no Brasil por Allergan Produtos Farmacêuticos, cujo…
Pictures, Preparations, and Living Processes: The Production of Immediate Visual Perception (Anschauung) in late-19th-Century Physiology
- ArtJournal of the history of biology
Studying the material culture of physiological image production reveals that technological resources such as telegraphy, photography, and even railways contributed to making physiological facts anschaulich and shows that the more traditional image techniques of anatomy played an important role in physiological lecture halls, especially when it came to displaying the details of vivisection experiments to the public.
Re-adaptation hypothesis: explaining health benefits of caloric restriction.
- MedicineMedical hypotheses
The experimental method and the problem of psychiatry as a science
- PhilosophyEpidemiologia e Psichiatria Sociale
No discussion of the experimental method can ignore Claude Bernard's 'Introduction to the Study of Experimental Medicine' (Bernard, 1927). Describing the 'true scientist', Bernard observes: «The true…
Holism and Reductionism in the Illness/Disease Debate
It is claimed that an adequate notion of medicine requires an integrative position that mediates between the analytic-reductionist and the normative-holistic tendencies the authors find therein, and that this is a necessary step to overcome today's trend to split evidence-based and clinical medicine.
Self-Construction, Self-Protection, and Self-Enhancement: A Homeostatic Model of Identity Protection
Abstract Self-protection and self-enhancement, once depicted as biases that impede accurate self-knowledge and hinder effective environmental control, have more recently been viewed as misbeliefs…
The sympathies of the body: functional organization and neuronal differentiation in the peripheral sympathetic nervous system
- BiologyCell and tissue research
A critical question now emerges for the integration of the diverse sympathetic neuron classes into neural circuits specific for these different target tissues to achieve the homeostatic regulation of the physiological ends affected.