Medical Cannabis for Neuropathic Pain

@article{Lee2018MedicalCF,
  title={Medical Cannabis for Neuropathic Pain},
  author={Gemayel Lee and Brittany Grovey and Timothy J. Furnish and Mark S Wallace},
  journal={Current Pain and Headache Reports},
  year={2018},
  volume={22},
  pages={1-12}
}
Purpose of ReviewMany cultures throughout history have used cannabis to treat a variety of painful ailments. Neuropathic pain is a complicated condition that is challenging to treat with our current medications. Recent scientific discovery has elucidated the intricate role of the endocannabinoid system in the pathophysiology of neuropathic pain. As societal perceptions change, and legislation on medical cannabis relaxes, there is growing interest in the use of medical cannabis for neuropathic… 
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49 Citations
Highly Influential Citations
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49 Citations

The Use of Medical Cannabis for Treatment of Chronic Neuropathic Pain: An Integrative Research Review
TLDR
The aim of this integrative research review (IRR) was to explore the efficacy of medical cannabis for chronic neuropathic pain treatment in patients who were 18 years and older in the last eight years from 2010 to 2018.
Cannabis for Chronic Pain: Challenges and Considerations
TLDR
The available scientific evidence is analyzed to address controversial questions that the current state of cannabis poses for health care professionals and chronic pain patients and sets the basis for a more open discussion about the role of cannabis in modern medicine for pain management.
Can Medical Cannabis Therapies be Cost-Effective in the Non-Surgical Management of Chronic Knee Pain?
TLDR
The study showed that MC may be a cost-effective strategy in the management of chronic knee pain; however, the evidence on the medical use of cannabis is limited and predominantly low-quality.
Efficacy of topical cannabinoids in the management of pain: a systematic review and meta-analysis of animal studies
TLDR
Preclinical animal studies provided low-quality evidence for peripherally administered cannabinoids to provide regional, antinociceptive effects, and the scarcity of high-quality human studies underscores the need to translate preclinical evidence into well-controlled human trials.
Chronic pain and medical cannabis: Narrative review and practice considerations in persons living with HIV
TLDR
Key literature for pain in PLWH and medical cannabis is summarized, pertinent dosage forms and dosing schedules are discussed, and safety and efficacy considerations for PLWH are summarized, and recommendations on cannabis rescheduling and pharmacists' and healthcare providers' roles are provided.
Clinical Outcome Data of First Cohort of Chronic Pain Patients Treated With Cannabis‐Based Sublingual Oils in the United Kingdom: Analysis From the UK Medical Cannabis Registry
TLDR
This study aimed to investigate the health‐related quality‐of‐life outcomes of patients with chronic pain who were prescribed CBMP oil preparations (Adven, Curaleaf International, Guernsey, UK).
Cannabidiol as a Treatment for Chronic Pain: A Survey of Patients’ Perspectives and Attitudes
TLDR
Most participants expressed a positive attitude about CBD products as a treatment option, reported positive outcomes when used for multiple different conditions, and would prefer to obtain information about and prescription for CBD from their physicians.
Cannabinoids in Pain Treatment: An Overview.
Topical Cannabinoids for Treating Chemotherapy-Induced Neuropathy: A Case Series
TLDR
This case series suggests that topical cannabinoids may be helpful for patients with chemotherapy-induced peripheral neuropathy who used topical creams containing the cannabinoids delta-nine-tetrahydrocannabinol (THC) and/or cannabidiol (CBD).
Medical Cannabis Use Reduces Opioid Prescriptions in Patients With Chronic Back Pain
TLDR
MC use reduces opioid prescription for patients with chronic back pain and improves pain and disability scores and improvement at follow-up as well.
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