Mediators leading to fibrosis - how to measure and control them in tissue engineering.

@article{Mu2010MediatorsLT,
  title={Mediators leading to fibrosis - how to measure and control them in tissue engineering.},
  author={Xd Mu and Ih Bellayr and Tj Walters and Yi-Gang Li},
  journal={Operative techniques in orthopaedics},
  year={2010},
  volume={20 2},
  pages={110-118}
}
Fibrosis is the result of an excessive amount of fibrous connective tissue deposited into the extracellular matrix (ECM) space of damaged tissues from injury or disease. Collagens, particularly types I and III are the main constituents of the fibrotic scar tissue as well as a mixture of fibrotic cells. Severely fibrotic tissue will develop chronic healing… CONTINUE READING