Mediator release in an isolated airway segment in subjects with asthma.

@article{Gravelyn1988MediatorRI,
  title={Mediator release in an isolated airway segment in subjects with asthma.},
  author={T R Gravelyn and Pauline M. Pan and William L. Eschenbacher},
  journal={The American review of respiratory disease},
  year={1988},
  volume={137 3},
  pages={641-6}
}
To determine if mediator release would occur in the airways of human subjects after exposure to a hyperosmolar stimulus, we challenged isolated airway segments in vivo with 900 mosmol sodium chloride using a specially designed double-balloon catheter. In order to determine if differences in mediator concentrations correlated with airway responsiveness or with atopy, we studied 3 separate groups: 6 atopic, asthmatic subjects; 6 atopic, nonasthmatic subjects; and 6 nonatopic, nonasthmatic normal… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

Similar Papers

Loading similar papers…