Mediation of prostaglandin f2 alpha-induced ocular surface hyperemia by sensory nerves in rabbits.

@article{Astin1997MediationOP,
  title={Mediation of prostaglandin f2 alpha-induced ocular surface hyperemia by sensory nerves in rabbits.},
  author={Matthew Astin and Johan W Stjernschantz},
  journal={Current eye research},
  year={1997},
  volume={16 9},
  pages={886-90}
}
PURPOSE Prostaglandin F2 alpha (PGF2 alpha) and several other prostaglandins cause surface hyperemia of the eye when applied topically. The purpose of the present study was to investigate the role of sensory nerves in prostaglandin-induced ocular hyperemia. METHODS The ophthalmic branch of the trigeminal nerve was unilaterally electrocoagulated in rabbits using a stereotaxic technique. Two weeks later the animals received bilaterally one drop of PGF2 alpha-isopropyl ester (PGF2 alpha-IE) at a… CONTINUE READING