Mediation of bone ingrowth in porous hydroxyapatite bone graft substitutes.

  title={Mediation of bone ingrowth in porous hydroxyapatite bone graft substitutes.},
  author={Karin Angela Hing and Serena M. Best and K Elizabeth Tanner and William Bonfield and Peter A. Revell},
  journal={Journal of biomedical materials research. Part A},
  volume={68 1},
Previous investigations have shown that both the early biological response and the mechanical properties of a porous hydroxyapatite bone graft substitute are highly sensitive to its pore structure. The objective of this study was to evaluate whether the pore structure continued to influence bone integration in the medium to long term. Two screened batches of porous hydroxyapatite (PHA) designated as batch A and batch B, with porosities of approximately 60 and 80%, respectively, were selected… CONTINUE READING
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