Mediation of Developmental Risk Factors for Psychosis by White Matter Microstructure in Young Adults With Psychotic Experiences.

@article{Drakesmith2016MediationOD,
  title={Mediation of Developmental Risk Factors for Psychosis by White Matter Microstructure in Young Adults With Psychotic Experiences.},
  author={Mark Drakesmith and Anirban Dutt and Leon Fonville and Stanley Zammit and Abraham Reichenberg and C. John Evans and Glyn Lewis and Derek K. Jones and Anthony S. David},
  journal={JAMA psychiatry},
  year={2016},
  volume={73 4},
  pages={396-406}
}
IMPORTANCE White matter (WM) abnormalities have been identified in schizophrenia at the earliest stages of the disorder. Individuals in the general population with psychotic experiences (PEs) may show similar changes, suggesting dysfunction due to aberrant neurodevelopment. Studying such people is a powerful means of understanding the nature of neurodevelopmental problems without the confound of clinical management and allows other potential risk factors associated with the schizophrenia… CONTINUE READING
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T Toulopoulou, N van Haren, X Zhang
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