Mediated Na(+)-independent transport of L-glutamate and L-cystine in 1- and 2-cell mouse conceptuses.

@article{Winkle1992MediatedNT,
  title={Mediated Na(+)-independent transport of L-glutamate and L-cystine in 1- and 2-cell mouse conceptuses.},
  author={Lon J. Van Winkle and D{\"o}rte Mann and H G Wasserlauf and Mahendra Patel},
  journal={Biochimica et biophysica acta},
  year={1992},
  volume={1107 2},
  pages={299-304}
}
L-Glutamate and L-cystine appeared to compete for transport via a mediated Na(+)-independent transport process in 1- and 2-cell conceptuses. Not only did these substances competitively inhibit each others' uptake by conceptuses, but their Ki values for inhibition were about equal to their Km values for transport in 1-cell conceptuses. Moreover, the transport process interacted strongly with L-amino acids that had 3-6 atoms in a chain between their negatively charged groups, whereas it… CONTINUE READING

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