Mediastinal large cell lymphoma. An uncommon subset of adult lymphoma curable with combined modality therapy.

@article{Jacobson1988MediastinalLC,
  title={Mediastinal large cell lymphoma. An uncommon subset of adult lymphoma curable with combined modality therapy.},
  author={Joseph O Jacobson and Alan C. Aisenberg and Louis Lamarre and Christopher G Willett and Rita M. Linggood and L M Miketic and Nancy Lee Harris},
  journal={Cancer},
  year={1988},
  volume={62 9},
  pages={
          1893-8
        }
}
Thirty adults with large cell lymphoma predominantly localized to the mediastinum diagnosed at the Massachusetts General Hospital between 1976 and 1985 were identified. The median age of the 20 females and 10 males was 34 years. All but one presented with symptoms due to an enlarging mediastinal mass, which was localized in 22 patients (73%) and exceeded 10 cm in maximal diameter in 65%. Superior vena cava syndrome and large pleural and pericardial effusions were common. Employing CHOP… CONTINUE READING
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