Medial temporal lobe glutathione concentration in first episode psychosis: A <ce:sup loc=pre>1</ce:sup>H-MRS investigation

@article{Wood2009MedialTL,
  title={Medial temporal lobe glutathione concentration in first episode psychosis: A <ce:sup loc=pre>1</ce:sup>H-MRS investigation},
  author={Stephen J. Wood and Gregor Emanuel Berger and R. Mark Wellard and T Proffitt and Christos Pantelis},
  journal={Neurobiology of Disease},
  year={2009},
  volume={33},
  pages={354-357}
}
Glutathione (GSH) is implicated in the pathophysiology of schizophrenia. Previous brain spectroscopy studies, however, have been inconsistent, and there is little data available from first episode psychosis patients. This study compared brain GSH in a first episode cohort (n=30) to controls (n=18), using magnetic resonance spectroscopy (MRS), examining a temporal lobe voxel. Short-echo (TE 30 ms) acquisition proton MRS was performed on a 3T clinical magnetic resonance scanner. Comparison of the… CONTINUE READING

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