Medial prefrontal cortex activation facilitates re-extinction of fear in rats.

Abstract

It has been suggested that reduced infralimbic (IL) cortical activity contributes to impairments of fear extinction. We therefore explored whether pharmacological activation of the IL would facilitate extinction under conditions it normally fails (i.e., immediate extinction). Rats received auditory fear conditioning 1 h before extinction training… (More)
DOI: 10.1101/lm.2070111

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